News Blog - 2024

December 9, 2024

Manuscript accepted for publication in Journal of Virology

186. Patil K, Ayyar B, Hayes N, Neill F, Bode L, Estes M, Atmar R, Ramani S (2024) 2′-Fucosyllactose Inhibits Human Norovirus Replication in Human Intestinal Enteroids. Journal of Virology (Accepted) [Research Article]

December 6, 2024

Manuscript accepted for publication in Global Pediatric Health

185. Shivakoti R, Laughton B, Shafiq M, Schoeman E, Glashoff R, Barnabas S, Fry S, Leu CS, Wang S, Bode L, Aldrovandi G, Kuhn L, Slogrove A (2024) A Longitudinal Observational Study of a Powder-Based Supplement for a Future Synbiotic Trial in Breastfed Children from South Africa. Global Pediatric Health (Accepted) [Research Article]

October 17, 2024

Manuscript accepted for publication in Frontiers in Immunology

184. Holzhausen E, Patterson WB, Wong BH, Kim S, Kupsco A, Howe CG, Bode L, Goran M, Alderete T (2024) Associations between human milk EV-miRNAs and oligosaccharide concentrations in human milk. Frontiers in Immunology (Accepted) [Research Article]

September 30, 2024

Manuscript accepted for publication in Frontiers in Nutrition

183. Fiecke C, Crimmins M, Hameed A, Sims C, Williams DK, Bode L, Martinez A, Andres A, Ferruzzi M (2024) Dietary modulation of human milk bioactives is associated with maternal FUT2 secretor phenotype: An exploratory analysis of carotenoids and polyphenol metabolites. Frontiers in Nutrition (Accepted) [Research Article]

September 15, 2024

Manuscript accepted for publication in JCI Insight

182. Pessentheiner AR, Spann NJ, Autran CA, Oh TG, Grunddal KV, Coker JKC, Painter C, Ramms B, Chiang AWT, Wang CY, Hsiao J, Wang Y, Quach A, Booshehri LM, Hammond A, Tognaccini C, Latasiewicz J, Willemsen L, Zengler K, de Winther MPJ, Hoffman HM, Philpott M, Cribbs AP, Oppermann U, Lewis NE, Witztum JL, Yu R, Atkins A, Downes M, Evans RM, Glass CK, Bode L, Gordts PLSM (2024) The Human Milk Oligosaccharide 3’Sialyllactose Reduces Low-grade Inflammation and Atherosclerosis Development in Mice. JCI Insight (Accepted) [Research Article, PubMed]

September 13, 2024

Work highlighted in The Economist

"HMOs, which arc known co have antiinflammatory effects, may be partly responsible. That has led to the idea thac HMOs could be used as therapeutics for diseases that involve inflammation. In a study in mice published in 2021, Lars Bode at the University of California, San Diego, and his colleagues reported that one HMO reduced the development of atherosclerosis, the blockage of arteries that leads to heart attack and stroke. Dr Bode says that in other experiments with mice, the results of which are yet to be published, HMOs have shown promise in treating arthritis and multiple sclerosis. Clinical trials with humans will be far more expensive."

"It is too early to tell whether any blockbuster drugs will result. But breast-milk scientists are starting to feel vindicated. For Bruce German from the University of

California, the neglect of breast milk will rank "as one of the great embarrassments

of scientific history."

Read the full article HERE! 

September 3, 2024

Manuscript accepted for publication in Cell Genomics

181. Johnson KE, Heisel T, Allert M, Fürst A, Yerabandi N, Knights D, Jacobs KM, Lock EF, Bode L, Fields DA, Rudolph MC, Gale CA, Albert FW, Demerath EW, Blekhman R (2024) Human milk variation is shaped by maternal genetics and impacts 1 the infant gut microbiome. Cell Genomics (Accepted) [Research Article]

August 30, 2024

Manuscript accepted for publication in Cell Reports Medicine

180. Masi AC, Beck LC, Perry JD' Granger CL, Hiorns A, Young GR, Bode L, Embleton ND, Berrington JE, Stewart  CJ (2024) Human milk microbiota, oligosaccharide profiles, and infant gut microbiome in preterm infants diagnosed with necrotising enterocolitis. Cell Reports Medicine (Accepted) [Research Article]

August 26, 2024

Manuscript accepted for publication in Clinical Nutrition ESPEN

179. Gurung M, Mulakala BK, Schlegel BT, Rajasundaram D, Shankar K, Bode L, Ruebel ML, Sims C, Martinez A, Andres A, Yeruva L (2024) Maternal immune cell gene expression associates with 1 maternal gut microbiome, milk composition and infant gut microbiome. Clinical Nutrition ESPEN (Accepted) [Research Article]

August 16, 2024

Manuscript accepted for publication in Open Forum Infectious Diseases

178. Rubinstein RJ, Lester Gutiérrez L, Toval-Ruíz C, Hammond K, Bode L, Vinjé J, Vilchez S, Becker-Dreps S, Bucardo F, Vielot NA, Reyes Y (2024) Epidemiology of pediatric astrovirus gastroenteritis in a Nicaraguan birth cohort. Open Forum Infectious Diseases, ofae465 [Research Article, PubMed]

July 24, 2024

Manuscript accepted for publication in The Journal of  Nutrition

177. Tripp P, Davis EC, Gurung M, Rosa F, Bode L, Fox R, LeRoith T, Simecka C, Seppo AE, Järvinen KM, Yeruva L  (2024) Infant microbiota communities and HMO supplementation independently and synergistically shape metabolite production and immune responses in healthy mice. The Journal of Nutrition (Accepted) [Research Article]

July 22, 2024

Manuscript accepted for publication in The American Journal of Clinical Nutrition

176. Ottino-González J, Adise S, Machle C, Babaei M, Mokthari P, Holzhausen E, Furst A, Yonemitsu C, Chalifour BN, Alderete T, Bode L, Goran MI (2024) Consumption of Different Combinations of Human Milk Oligosaccharides in the First 6 Months of Infancy is Positively Associated with Early Cognition at 2 Years of Age in a Longitudinal Cohort of Latino Children. The American Journal of Clinical Nutrition (Accepted) [Research Article]

July 15, 2024

Manuscript accepted for publication in Cell

175. Shenhav L, Fehr K, Reyna ME, Petersen C, Dai DLY, Dai R, Breton V, Rossi L, Smieja M, Simons E, Silverman MA, Levy M, Bode L, Field CJ, Marshall JS, Moraes TJ, Mandhane PJ, Turvey SE, Subbarao P, Surette MG, Azad MB (2024) Microbial colonization programs are structured by breastfeeding and guide healthy respiratory development. Cell (Accepted) [Research Article]

July 13, 2024

Manuscript accepted for publication in Pediatric Research

174. Schulkers Escalante K, Bai-Tong S, Allard SM, Ecklu-Mensah G, Sanchez C, Song CJ, Gilbert J, Bode L, Dorrestein P, Knight R, Gonzalez DG, Leibel SA, Leibel SL (2024) The Impact of Breastfeeding on the Preterm Infant’s Microbiome and Metabolome: A Pilot Study. Pediatric Research (Accepted) [Research Article]

June 3, 2024

Manuscript accepted for publication in Nutrients

173. Mokhtari P, Schmidt KA, Zamanian H, Babaei M, Machle CJ, Trifonova D, Alderete TL, Holzhausen EA, Ottino-González J, Chalifour BN, Jones RB, Furst A, Yonemitsu C, Bode L, Goran MI (2024) Maternal Diet Associated with Human Milk Oligosaccharide Abundances in Latina Women. Nutrients (Accepted) [Research Article]

May 8, 2024

Manuscript accepted for publication in Nature Communications

172. Ambalavanan A, Chang L, Choi J, Zhang Y, Stickley SA, Fang ZY, Miliku K, Robertson B, Yonemitsu C, Turvey SE, Mandhane PJ, Simons E, Moraes TJ, Anand SS, Paré G, Williams JE, Murdoch BM, Otoo GE, Mbugua S, Kamau-Mbuthia EW,  Kamundia EW, Gindola DK, Rodriguez JM, Pareja RG, Sellen DW, Moore SE, Prentice AM, Foster JA, Kvist LJ, Neibergs HL, McGuire MA, McGuire MK, Meehan CL, Sears MR, Subbarao P, Azad MB, Bode L, Duan Q (2024) Human milk oligosaccharides are associated with maternal genetics and respiratory health of human milk-fed children. Nature Communications (Accepted) [Research Article]

April 14, 2024

Manuscript accepted for publication in Breastfeeding Medicine

171. Furst A, Ford B, Hentschel H, Bode L (2024) Human Milk Oligosaccharides in Antenatal Colostrum: A Case Study. Breastfeeding Medicine (Accepted) [Research Article]

April 13, 2024

Manuscript accepted for publication in Nutrients

170. Ong ML, Cherkerzian S, Bell KA, Berger PK, Furst A, Sejane K, Bode L, Belfort MB (2024) Human Milk Oligosaccharides, Growth, and Body Composition in Very Preterm Infants. Nutrients (Accepted) [Research Article]

April 9, 2024

Manuscript accepted for publication in Journal of Perinatology

169. Schinkel ER, Nelson ER, Kim J, Perrin M, Dyer R, Elango R, Bode L, Dallas DC, Lueangsakulthai J, Briere CE, Taylor SN (2024) Point-of-care Human Milk Concentration by Passive Osmosis: Comprehensive Analysis of Fresh Human Milk Samples. Journal of Perinatology (Accepted) [Research Article]

March 21, 2024

Manuscript accepted for publication in Cell Host & Microbes

168. Selma-Royo M, Dubois L, Manara S, Armanini F, Cabrera-Rubio R, Valles-Colomer M, Parra-Llorca A, Escuriet R, Martinez-Costa C, Bode L, Segata N, Collado MC (2024) Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year. Cell Host & Microbes (Accepted) [Research Article]

March 14, 2024

Manuscript accepted for publication in Scientific Reports

167. Naik NC, Holzhausen EA, Chalifour BN, Coffman MM, Lurmann F, Goran MI, Bode L, Alderete TL (2024) Air pollution exposure may impact the composition of human milk oligosaccharides. Scientific Reports (Accepted) [Research Article]

March 4, 2024

Manuscript accepted for publication in mSystems

166. Gurung M, Schlegel B, Rajasundaram D, Fox R, Bode L, Yao T, Lindemann S, LeRoith T, Read Q, Simecka C, Carroll L, Andres A, Yeruva L (2024) Microbiota from human infants consuming secretor or non-secretor mothers’ milk impacts the gut and immune system in mice. mSystems (Accepted) [Research Article

February 29, 2024

Manuscript accepted for publication in Frontiers in Nutrition

165. Sims C, Saben J, Martinez A, Sobik SR, Crimmins MR, Bulmanski JE, Turner D, Furst A, Jansen LT, Bode L, Andres A. (2024) A Mediterranean diet plan in lactating women with obesity reduces maternal energy intake and modulates human milk composition: a feasibility study. Frontiers in Nutrition (Accepted) [Research Article]

February 20, 2024

Manuscript accepted for publication in Nutrients

164. Renwick S, Rahimi K, Sejane K, Bertrand K, Chambers C, Bode L (2024) Consistency and variability of the human milk oligosaccharide profile in repeat pregnancies. Nutrients (Accepted) [Research Article]

February 15, 2024

Bode lab welcomes Dr. Monica Lores Guerrero visiting from Mexico

January 31, 2024

Bode lab welcomes TEP Awardee Laasya Devi Annapureddy

Congratulations to Laasya Devi Annepureddy, a graduate student at Dartmouth College, for receiving a TEP Award supported by the Family Larsson-Rosenquist Foundation!

We look forward to welcoming you to our lab here at UC San Diego to work on a project on Human Milk Oligosaccharides (HMOs) and adipocyte metabolism in collaboration with Britt Goods and Philip Gordts, PhD.

Laasya follows in the footsteps of Klara McClunan from Stellenbosch University, South Africa, Kelsey Cochrane from UBC in Vancouver, Canada, and Sara Shama from Sick Kids in Toronto, Canada, who all visited our lab on a TEP fellowship over the last few years.

January 17, 2024

Manuscript accepted for publication in Scientific Reports

163. Becker M, Fehr K, Goguen S, Miliku K, Field C, Roberston B, Yonemitsu C, Bode L, Simons E, Marshall J, Dawod B, Mandhane P, Turvey SE, Moraes TJ, Subbarao P, Rodriguez N, Aghaeepour N, Azad MB (2024) Multimodal machine learning for modeling infant head circumference, mothers’ milk composition, and their shared environment. Scientific Reports (Accepted) [Research Article]